Lipids and Lipid Derivatives
Medchemexpress LLC Procyanidin B2 | 29106-49-8 | 578.52 | 25 MG
Procyanidin B2 is a natural flavonoid known for its anti-cancer and antioxidant properties, making it valuable for various research applications. It is intended for research use only.
- Exhibits antiproliferative activity in MCF-7 cells.
- Inhibits NLRP3 inflammasome activation in human umbilical vein ECs (HUVECs).
- Reduces reactive oxygen species (ROS).
- Protects against cerebral ischemia-induced infarct volume and brain edema.
- Improves neurological functional outcomes and regulates blood-brain barrier permeability.
- Attenuates cerebral ischemia-induced tight junction degradation, mitochondrial depolarization, and intracellular oxidative stress.
- Increases Nrf2 activation and expression of HO-1, GSTα, and NQO1 proteins.
Cayman Chemical Glycidyl Palmitate, Purity: ≥98%, CAS: 7501-44-2, 50 mg
A glycidyl fatty acid ester; has been found in palm and corn oils
Medchemexpress LLC Zinc stearate 1kg
Zinc stearate is a Zinc distearate Zinc stearate can be used as an excipient such as lubricants for tablets and capsules Pharmaceutical excipients or pharmaceutical auxiliaries refer to other chemical substances used in the pharmaceutical process other than pharmaceutical ingredients Pharmaceutical excipients generally refer to inactive ingredients in pharmaceutical preparations which can improve the stability solubility and processability of pharmaceutical preparations Pharmaceutical excipients also affect the absorption distribution metabolism and elimination (ADME) processes of co-administered drugs[1][2]
Medchemexpress LLC 2-Naphthyl laurate 500mg
2-Naphthyl Laurate is a biochemical reagent that can be used as a biological material or organic compound for life science related research
Medchemexpress LLC Itaconate-alkyne | 2454181-83-8 | 98.0% | C13H18O4 | 10MG
Itaconate-alkyne is an alkyne-tagged bioorthogonal probe designed for quantitative and site-specific chemoproteomic profiling of itaconation in living cells. As a functional analogue of itaconate, it enables labeling of bona fide itaconate targets and is compatible with click-chemistry workflows.
- Contains alkyne group for copper-catalyzed azide-alkyne cycloaddition.
- Enables quantitative and site-specific chemoproteomic profiling.
- Functions as a structural analogue of itaconate with comparable anti-inflammatory effects.
- High purity solid form for reliable experimental results.
- Available in multiple small-scale packaging sizes suitable for laboratory use.
- Compatible with standard click-chemistry reagents and protocols.
Cayman Chemical Myristoleic Acid methyl ester, Purity: ≥98%, CAS: 56219-06-8, 100 mg
A more hydrophobic form of the free acid, a cytotoxic component from the fruit extract of S. repens
Medchemexpress LLC Methyl myristate | 124-10-7 | 242.40 | 5 G
Methyl myristate is a saturated fatty acid methyl ester produced through the esterification of myristic acid. It has been observed to exhibit a high melanin induction in B16F10 melanoma cells.
- In vitro activity: Methyl myristate is a component of petroleum ether extract.
- This extract has demonstrated the ability to reduce acetylcholine and ergot alkaloid-induced uterine contractions in isolated rat uteri, indicating uterine relaxation activity.
eMolecules 37779-49-0 | 3-Oxo-4-phenylbutyric acid methyl ester | Combi-Blocks | MFCD03424746 | 192.214 | C11H12O3 | 98.000 | COC(=O)CC(=O)Cc1ccccc1 | 25g | 296395714
3-Oxo-4-phenylbutyric acid methyl ester | Combi-Blocks | 37779-49-0 | MFCD03424746 | 192.214 | C11H12O3 | 98.000 | COC(=O)CC(=O)Cc1ccccc1 | 25g | 296395714
eMolecules 474645-27-7 | Monomethyl auristatin E | Combi-Blocks, Inc. | MFCD22124498 | 717.993 | C39H67N5O7 | 95.000 | CC[C@H](C)[C@@H]([C@@H](CC(=O)N1CCC[C@H]1[C@H](OC)[C@@H](C)C(=O)N[C@H](C)[C@@H](O)c1ccccc1)OC)N(C)C(=O)[C@@H](NC(=O)[C@@H](NC)C(C)C)C(C)C | 1g | 797032924
Monomethyl auristatin E | Combi-Blocks, Inc. | 474645-27-7 | MFCD22124498 | 717.993 | C39H67N5O7 | 95.000 | CC[C@H](C)[C@@H]([C@@H](CC(=O)N1CCC[C@H]1[C@H](OC)[C@@H](C)C(=O)N[C@H](C)[C@@H](O)c1ccccc1)OC)N(C)C(=O)[C@@H](NC(=O)[C@@H](NC)C(C)C)C(C)C | 1g | 797032924
Medchemexpress LLC Ethyl acetoacetate-13C | 61973-42-0 | 98.6% | 131.13 | 100 MG
Ethyl acetoacetate-13C is a 13C labeled ester extensively used as an intermediate in the synthesis of various compounds. It is also identified as an inhibitor of bacterial biofilm, and can be utilized as a tracer and an internal standard for quantitative analysis via methods such as NMR, GC-MS, or LC-MS.
- Used as a tracer
- Serves as an internal standard for quantitative analysis
- Incorporates carbon-13, a stable heavy isotope, for quantitation during drug development
Medchemexpress LLC Ethyl palmitate | 628-97-7 | 50 G
Ethyl palmitate (Ethyl hexadecanoate) is a Chikungunya virus (CHIKV) inhibitor with an EC50 value of 0.0068 μM. It demonstrates anti-inflammatory activity by reducing levels of TNF-α, IL-6, and NF-κB.
- Inhibits expression and viral activity of CHIKV virus E2 protein.
- Reduces plasma levels of TNF-α and IL-6 in endotoxemic rats.
- Decreases NF-κB expression in liver and lung tissues.
- Ameliorates histopathological changes caused by LPS in a rat model of endotoxemia.
Cayman Chemical Betamethasone 17-valerate, Purity: ≥98%, CAS: 2152-44-5, 500 mg
A glucocorticoid with anti-inflammatory activity; inhibits the binding of the radiolabeled glucocorticoid dexamethasone to human epidermis and mouse skin (IC50s = 5 and 6 nM, respectively); topical application of a 0.12% ointment blocks increases in ear weight in a rat model of ear edema induced by croton oil
Medchemexpress LLC Mk-0812 succinate | 851916-42-2 | 99.94% | C28H40F3N3O7 | 100 MG
MK-0812 Succinate is a potent and selective CCR2 antagonist with high affinity. It completely blocks all MCP-1 mediated responses in a concentration-dependent manner. It also inhibits 125I-MCP-1 binding on isolated monocytes. The compound blocks the shape change response to exogenous MCP-1 and reduces the frequency of Ly6G-Ly6Chi monocytes in peripheral blood in vivo.
- Potent and selective CCR2 antagonist
- High affinity at CCR2
- Blocks all MCP-1 mediated responses
- Inhibits 125I-MCP-1 binding on isolated monocytes
- Reduces Ly6G-Ly6Chi monocytes in peripheral blood in vivo
Medchemexpress LLC Aluminum stearate (octadecanoate aluminum) | 637-12-7 | MFCD00036389 | 293.47 g/mol | C18H36O2·1/3Al | 500 G
Aluminum stearate (octadecanoate aluminum) is a fatty-acid metal salt used as a thickener and lubricant in cosmetic and industrial formulations. Supplied as a white to off-white solid, it is typically used to increase viscosity and improve texture in oil-based products.